For the first time in Ukraine cardiac operations on the reason heart lesions were performed (M.M. Amosov).
By now more than 85 000 cardiac operations were performed.
For the first time in Ukraine the operation with artificial blood circulation was fulfilled (M.M. Amosov).
By now more than 35 000 such operations are done.
The activities on development of medical cybernetics were begun.
For the first time in Ukraine the artificial kidney was applied.
For the first time in the Soviet Union the mitral valve replacement was performed (M.M.Amosov).
By now more than 12 000 operations of heart valves replacements had been fulfilled.
For the first time in the Soviet Union operations on the heart in the hyperbaric oxygen chamber were performed (L.N. Sidorenko, L.P.Chepkiy).
For the first time in the world the antithrombic artificial heart valve prosthesis was created and introduced into practice (M.M. Amosov).
For the first time in Ukraine the aorta-coronaries bypass grafting operations were fulfilled (G.V. Knyshov).
By now about 3 000 of a such operations were executed.
For the first time in Ukraine the method of cardioplegy was applied (V.B. Maksymenko).
For the first time in Ukraine the component infusion hemotherapy was used in cardiac surgery (A.M. Kryshtof).
For the first time in the Soviet Union the balloon angioplasty at pulmonary artery stenosis was applied (Yu.V.Panichkin).
By now more than 2 500 endovascular operations were performed on the reason of congenital and acquired heart lesions.
For the first time in Ukraine the surgical correction of tachisystolic forms of arrhythmia was applied (G.V. Knyshov).
For the first time in Ukraine the intraaortic balloon contrapulsation and synchronized artificial circulatory assistance
for support of the failing heart and lung were applied (V.B. Maksymenko).
The first cardiac operations in newborns were made (I.N. Yemets). Now more 300 such operations were executed.
For the first time in the world the computer simulator for heart-lung bypass was developed (E.A. Nastenko).
The work was awarded on 5th European Congress on Extracorporeal Circulation Technologies, Aries, France.
The fundamental mechanisms of oxygen mass transfer in human organism ware studied.
The new information technology for restoration of the functional characteristics of human physiological systems was created.
With a great number of physiological characteristics earlier revealed only in experiments were obtained.
The effective system of surgical treatment and immunocorrection at infectious endocarditis was developed.
The greatest experience in the world is accumulated - more than 1 000 operations.
The realization of the "Golden Section" principle in blood circulation regulation (G.V.Knyshov, E.A.Nastenko, B.L.Palets).
The original theory of obstructive hypertrophic cardiopathy pathogenesis was created. On its basis the original method of treatment with two-chamber cardiac pacing was developed (G.V.Knyshov).
The resonance phenomenon at oscillatory processes in blood circulatory system is studied.
The methods of optimization of heart and lung extracorporeal support are developing.
Fundamental researches in the field of development of medical engineering and biomaterials are executed.
Development of telemedical technologies in area of cardiology and cardiac surgery. Participation in the first medical telebridges.
Operation of coronary arteries-aortic bypass grafting on the beating heart was fulfilled.
The researches in area of synergetics. Investigations of nonlinear dynamics of cardiovascular system.
Elaboration of the original method of pharmacological cold myocardial protection with the use of artificial blood.
The researches of systemic oxygen transport and modeling of microvascular network complex behavior with cellular automata (E.A. Nastenko).
Method of cardiac operations without the use of a donor blood was elaborated.
The algorythm of diagnostics and urgent treatment of primary heart tumors (G.V. Knyshov, R.M. Vitovsky).
Creation of principally new theory of forming of the heart myxomas (V.P. Zakharova, E.V. Rudenko).
The use of hyperthermic heart-lung bypass in the treatment of infective endocarditis and myocardial protection with the artificial blood (perftorane).
Elaboration of the method of open-heart operations without the donor blood.
The off-pump aorta-coronary by-pass grafting operations on a beating heart (without heart-lung bupass) were developed that allowed twice exceed the high-quality indexes of the CABG.
The method of the left ventricle aneurysm correction was developed in Institute, it allowed to lower mortality to 1,4%.
A method of diagnostics and treatment of congenital heart diseases with concomitant atrial izomerizmom and the mirror image of the internal organs was elaborated; method of transcatheter treatment of atrial fibrillation, which can eliminate the arrhythmia in 99.3% cases was applied with virtually no complications.